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精萘毒理学资料及环境行为

来源:http://www.jnjdbc.cn/ 日期:2024-04-22 发布人:创始人

毒性:属低毒类。

Toxicity: Belongs to the low toxicity category.

急性毒性:LD50490mg/kg(大鼠经口);人经口5g,白内障及肾损害;人经口5~15g,致死;儿童经口2.0g/2日,致死。

Acute toxicity: LD50490mg/kg (orally administered to rats); Oral administration of 5g, cataracts and kidney damage; 5-15g per person via oral route, fatal; Children die from oral ingestion of 2.0g/2 per day.

亚急性和慢性毒性:兔经口1g/(kg·天),3天,见晶状体浑浊,20天后形成白内障。兔吸入饱和蒸气2小时/天,2~3个月,红细胞先增多后减少;400~500mg/m3,4小时/天,5个月,见晶状体浑浊。小鼠吸入60~500mg/m3,5个月,条件反射紊乱,尸检见呼吸系统损害。

Subacute and chronic toxicity: 1g/(kg · day) orally administered to rabbits for 3 days, with lens opacity observed and cataracts formed 20 days later. Rabbits inhale saturated vapor for 2 hours/day, 2-3 months, and red blood cells first increase and then decrease; 400-500mg/m3, 4 hours/day, 5 months, with lens opacity observed. Mice inhaled 60-500mg/m3 for 5 months, with disrupted conditioned reflexes and respiratory system damage observed at autopsy.

致突变性:细胞遗传学分析:仓鼠卵巢30mg/L。姊妹染色单体交换:仓鼠卵巢15mg/L。

Mutagenicity: Cytogenetic analysis: Hamster ovary 30mg/L. Sister chromatid exchange: Hamster ovary 15mg/L.

生殖毒性:小鼠经口最低中毒剂量(TDL0):2400mg/kg(孕7~14天),影响活产指数,影响存活指数(如活产在第4天时的存活数)。

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Reproductive toxicity: The lowest oral toxic dose (TDL0) in mice is 2400mg/kg (7-14 days of pregnancy), which affects the live birth index and the survival index (such as the number of live births on the 4th day).

致癌性:大鼠皮下最低中毒剂量(TDL0):3500mg/kg(12周,间歇),疑致肿瘤剂,致淋巴瘤,包括何杰金氏病,致子宫肿瘤。小鼠吸入最低中毒浓度(TCL0):30ppm(6小时)(2处,间歇),致肿瘤,致肺肿瘤。

Carcinogenicity: Subcutaneous minimum toxic dose (TDL0) in rats: 3500mg/kg (12 weeks, intermittent), suspected to be a tumor causing agent, causing lymphoma, including Hodgkin's disease, and causing uterine tumors. Mouse inhalation of the lowest toxic concentration (TCL0): 30ppm (6 hours) (2 places, intermittent), causing tumors and lung tumors.

在环境中的迁移几个实验证明了多环芳烃(PAHs)的可生物降解性。低分子量的多环芳香烃(PAHs)如萘、苊、苊烯在实验研究中均能快速地被降解。初始浓度为5~10mg/L的液体,在7天之内有90%以上的多环芳香(PAHs)被生物降解。高分子量的多环芳香烃(PAHs)如荧蒽、苯并(a)蒽、屈、苯并(a)芘和和蒽等很难被 生物降解。

Several experiments on migration in the environment have demonstrated the biodegradability of polycyclic aromatic hydrocarbons (PAHs). Low molecular weight polycyclic aromatic hydrocarbons (PAHs) such as naphthalene, acenaphthene, and acenaphthene can be rapidly degraded in experimental studies. A liquid with an initial concentration of 5-10mg/L can biodegrade over 90% of polycyclic aromatic hydrocarbons (PAHs) within 7 days. High molecular weight polycyclic aromatic hydrocarbons (PAHs) such as fluoranthene, benzo (a) anthracene, quinone, benzo (a) pyrene, and anthracene are difficult to biodegrade.

危险特性:遇明火、高热可燃。燃烧时放出有毒的刺激性烟雾。与强氧化剂如铬酸酐、氯酸盐和高锰酸钾等接触,能发生强烈反应,引起燃烧或爆炸。粉体与空气可形成爆炸性混合物,当达到一定的浓度时,遇火星会发生爆炸。

Hazardous characteristics: flammable in the presence of open flames and high heat. Toxic and irritating smoke is emitted during combustion. When in contact with strong oxidants such as chromic anhydride, chlorate, and potassium permanganate, a strong reaction can occur, causing combustion or explosion. Powder and air can form explosive mixtures, and when they reach a certain concentration, they will explode when encountering Mars.

燃烧(分解)产物:一氧化碳、二氧化碳。

Combustion (decomposition) products: carbon monoxide, carbon dioxide.

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